The world of aesthetic medicine innovation has seen many treatments come and go, yet few have stirred as much attention as Rejuran.
Known as a skin rejuvenation therapy, it is different because it focuses on tissue regeneration therapy rather than masking aging signs. Instead of providing short-lived cosmetic changes, it activates the skin’s natural healing ability.
Rejuran was first developed in South Korea, a region famous for driving skincare advancements. Scientists discovered that salmon DNA extract contains unique polynucleotide injections compatible with human DNA.
These fragments encourage healing without immune rejection, making Rejuran a biocompatible skincare breakthrough.
Since its introduction, Rejuran has gained strong popularity across Asia and Europe, and its reputation continues to expand globally as a natural skin healer. Let’s dive in!
How Rejuran Works in Skin Regeneration
The core science behind Rejuran lies in injectable polynucleotides. When injected into the dermis, these molecules serve as structural scaffolding, supporting the dermal repair mechanism.
This process awakens the body’s natural healing, triggering fibroblast activation. Fibroblasts are cells responsible for building collagen and repairing damaged tissues, which are vital for youthful and firm skin.
The treatment also improves skin microcirculation, which enhances the delivery of oxygen and nutrients. At the same time, it reduces inflammation, calming irritated or sensitive skin.
By supporting extracellular matrix repair, Rejuran rebuilds the framework that keeps skin elastic and resilient. Unlike hyaluronic acid fillers, which focus on hydration or volume, Rejuran truly works as a cellular repair treatment with long-lasting outcomes.
Different Types of Rejuran Treatments

To address different skin concerns, four main formulations were developed.
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Each type of Rejuran has specific strengths, allowing dermatologists to tailor treatments to the patient’s needs.
Type | Formula Purpose | Best Suited For | Unique Features |
---|---|---|---|
Rejuran Healer | General skin repair therapy | Fine lines, overall rejuvenation | Improves texture and strengthens skin barrier |
Rejuran S | Thicker cosmetic injectables | Acne scar improvement | Designed for deeper skin damage and depressed scars |
Rejuran I | Gentle non-surgical rejuvenation | Sensitive skin rejuvenation near the eyes | Improves under-eye wrinkles and thin skin |
Rejuran HB | Blend with hyaluronic acid | Skin hydration booster | Combines repair with added hydration for dull, tired skin |
These variations allow for customized aesthetic clinic treatments, addressing everything from wrinkles to acne scars. The adaptability makes Rejuran a versatile choice in cosmetic dermatology.
Key Benefits and Results of Rejuran Therapy
The results of Rejuran are often described as subtle but transformative. Instead of changing facial features, it restores what the skin has lost over time. Patients commonly notice firmer skin, smoother tone, and reduced fine lines.
Over multiple sessions, it delivers a brighter and more youthful appearance.
Another significant benefit lies in its ability to work as a scar healing solution. Rejuran S has proven effective in reducing acne scars, something many patients struggle with for years.
Beyond scars, its ability to improve hydration makes it a powerful anti-aging solution, leaving the complexion plumper and healthier without the “overfilled” look that some injectables create.
These natural-looking results are why so many people choose it over temporary fixes.
Treatment Procedure and Patient Experience
A Rejuran session typically lasts 30 to 45 minutes. The doctor begins by applying numbing cream to reduce discomfort. Using micro-needles, the practitioner injects injectable polynucleotides into the skin at multiple points.
The procedure may create small bumps that resemble mosquito bites, but these fade within one or two days.
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Results do not appear overnight. Patients usually see early changes in about two to four weeks, while optimal effects occur after three to four sessions.
Maintenance sessions are recommended once or twice a year. Compared to other minimally invasive procedures, the downtime is very short, which makes it attractive for those with busy lifestyles.
Quick Details About Rejuran:
Factor | Detail |
---|---|
Session Duration | 30–45 minutes |
Pain Level | Mild, reduced by numbing cream |
Downtime | 1–2 days |
Initial Treatment Plan | 3–4 sessions |
Maintenance | Every 6–12 months |
Best Starting Age | Late 20s onwards |
This predictable routine is why many patients consider Rejuran one of the most reliable aesthetic skin repair options available today.
Who Should Consider Rejuran?
Rejuran is designed for people who want long-lasting skin improvements without dramatic or artificial changes.
Adults in their late 20s or older with early signs of aging benefit most, as do those with uneven skin texture or scars. It is often chosen by people looking for a skin rejuvenation therapy that feels natural.
Those with sensitive skin conditions also respond well to Rejuran, particularly when using Rejuran I. Its gentle formulation is perfect for delicate areas like under the eyes.
Whether the goal is to soften wrinkles, improve scars, or gain a skin hydration booster, Rejuran offers something for nearly every skin type.
Risks, Side Effects, and Safety Considerations
Although Rejuran is considered safe, no treatment is entirely risk-free. Common side effects include temporary redness, swelling, or small bruises at injection sites. These usually resolve within a couple of days and are similar to other cosmetic injectables.
Allergic reactions are extremely rare due to the close match of salmon DNA extract with human DNA. This makes it a reliable biocompatible skincare option.
Choosing an experienced doctor for aesthetic clinic treatments is essential. Proper injection technique minimizes side effects and ensures the best outcome.
Cost and Market Popularity of Rejuran
The cost of Rejuran depends on the clinic, location, and formula used. On average, a single session ranges between $300 and $700.
A full treatment plan with three or four sessions may total $1,000 to $2,500. Maintenance sessions once or twice yearly add to the overall investment.
Despite the cost, patients often view it as worthwhile for long-term skin health. Rejuran’s popularity has grown steadily since its launch. The global adoption of Rejuran reflects a broader shift in the beauty industry.
Instead of chasing temporary solutions, people now want skin repair therapy that lasts. This aligns with the global skincare trend toward natural and science-driven treatments.
Comparisons and Future Outlook of Rejuran
Rejuran differs significantly from Botox and fillers. Botox works by relaxing muscles to smooth wrinkles, while fillers restore lost volume.
Both offer fast but temporary fixes. Rejuran, however, focuses on the wound healing process, stimulating extracellular matrix repair and producing genuine improvements in skin structure.
The regenerative aesthetics future looks promising. Studies are exploring the combination of Rejuran with microneedling, lasers, and even hair restoration therapies. Scar reduction therapy and sensitive skin rejuvenation remain strong areas of research.
Experts believe that treatments based on tissue regeneration therapy will eventually become the cornerstone of modern cosmetic dermatology.
Comparison Table:
Treatment | Mechanism | Best For | Duration |
---|---|---|---|
Botox | Muscle relaxation | Dynamic wrinkles | 3–6 months |
Fillers (HA) | Volume & hydration | Deep wrinkles, hollow areas | 6–12 months |
Rejuran | Cellular repair treatment | Fine lines, scars, texture | 6–12 months, cumulative |
Conclusion:
Rejuran has changed the way people view cosmetic treatments. Rather than simply covering imperfections, it works as a skin repair therapy.
Through fibroblast activation and dermal repair mechanism, it helps the skin rebuild itself. Patients gain a refreshed look that feels natural and lasting.
With its ability to deliver scar healing solutions, skin hydration booster effects, and overall skin texture refinement, Rejuran stands out among cosmetic injectables.It represents a movement toward healthier, stronger skin supported by science.
As more people choose non-surgical rejuvenation, Rejuran will continue to lead the way in aesthetic medicine innovation.
FAQs
How soon will I see results from Rejuran?
Most people notice early results within two to four weeks. The best improvements appear after three or four sessions, as the skin gradually repairs itself.
Is Rejuran safe for sensitive skin?
Yes. Treatments like Rejuran I are specially designed for sensitive skin rejuvenation, especially around the eyes. Its biocompatible skincare base makes it gentle yet effective.
Can Rejuran be combined with other treatments?
Absolutely. Many clinics combine it with microneedling, lasers, or fillers. This creates a more complete aesthetic skin repair plan with enhanced outcomes.
How long do Rejuran results last?
Results typically last six to twelve months. Maintenance sessions every six to twelve months help sustain improvements in long-term skin health.
Is Rejuran painful?
Discomfort is minimal. Numbing cream is applied before the session. Patients usually describe it as a tolerable minimally invasive procedure with quick recovery.